Fig. 4

MALBoost results for AP2-G GRN. A The number of ChIP-targets for AP2-G and AP2-I that were within the top putative target genes of AP2-G either by importance or using top interactors were tested for significant overrepresentation using a two-tailed Fisher’s exact test (#P < 0.1, *P < 0.05). B Distribution of importance over Pearson correlation for the investigated genes (5142) with ChIP-targets (ChIP) and ChIP-targets that were differentially transcribed following AP2-G knock down (ChIP-diff) highlighted. Solid line =  > 30 importance threshold, dashed line = Top 100 interactors. C Genes above the 30 importance threshold were ordered by decreasing importance and Pearson correlation shown along with hits in AP2-G ChIP-seq, differential transcripts in the AP2-G knockdown, EBA175 KO, and the stage at which the transcripts peak in abundance (Additional File 1)