Fig. 2
Effects of SPAQ and SPAQ + AZ on Plasmodium falciparum infection in humans. A The prevalence (± 95% CI) of asexual stage parasitaemia for each treatment and the control group. B The density of asexual stage parasites (number of parasites/µl of blood in infected blood collections) for each treatment and the control group. Each point represents a blood sample from P. falciparum-positive slides. The horizontal line represents the median value of parasite density for each of the three groups, and the upper and lower boundaries of the box indicate the 75th and 25th percentile, respectively. Note that the y-axis is on a log10 scale. C The prevalence (± 95% CI) of gametocyte for each treatment and the control group as measured by microscopy; D The density of gametocyte (number of gametocytes/µl of blood in gametocyte-positive blood collections) for each group. Note that the y-axis is on a log10 scale. The presence and number of asexual stages or gametocytes in samples was determined by microscopic observation. Different lowercase letters above the bars denote statistically significant differences based on multiple pair-wise post-hoc tests. NS: Not significant