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Fig. 3 | Malaria Journal

Fig. 3

From: Effect of seasonal malaria chemoprevention plus azithromycin on Plasmodium falciparum transmission: gametocyte infectivity and mosquito fitness

Fig. 3

Effects of SPAQ and SPAQ + AZ on Plasmodium falciparum infectivity from humans to mosquitoes. A The proportion (± 95% CI) of feeds resulting in at least one successful mosquito infection (i.e., a minimum of one mosquito harbouring a minimum of one oocyst) for each treatment group. There were 171 feeds for the control, 182 for SPAQ and 190 for the SPAQ-AZ treatment and an average of 38.87 ± 0.48 (median = 41, range = 5–51) mosquitoes were dissected per feed (n total = 21,108 mosquitoes). B Oocyst prevalence (± 95% CI) defined as the total number of mosquitoes fed with blood drawn from each study group harbouring at least one oocyst in their midgut out of the number of dissected mosquitoes from this group. C Oocyst density defined as the number of oocysts observed in infected mosquitoes for each group. The horizontal line represents the median value of density for each of the three study groups, and the upper and lower boundaries of the box indicate the 75th and 25th percentile, respectively. D Oocyst density following infectious feeds on samples from the control group, SPAQ group and SPAQ + AZ group. Note that the y-axis on panels (C) and (D) is on a log10 scale. Different lowercase letters above the bars denote statistically significant differences based on multiple pair-wise post-hoc tests. NS: Not significant

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