Table 3 Composition of liposomes-based vaccines for malaria prophylaxis

R32tet₃₂

DMPC: cholesterol: dicetylphosphate: lipid A

DMPC: cholesterol: DMPG: lipid A

DMPC: cholesterol: dicetylphosphate: lipid A (± alum)

DMPC: cholesterol: DMPG: lipid A (± alum)

1:0.75:0.1:0.02

0.9:0.75:0.1:0.02

1:0.75:0.1:0.02 (± 20 nmol/µmol of phospholipid)

0.9:0.75:0.1:0.02 (± 20 nmol/µmol of phospholipid)

[226, 227]

R32NS1₈₁

Cholesterol: DMPC: DMPG (± MPLA)

0.75:0.9:0.1 (± 52.6 µg/µmol lipid)

[228]

R32NS1

DMPC: DMPG: cholesterol: lipid A

1.8:0.2:1.5:0.04

1.8:0.2:1.5:0.005

[229]

RTS,S

DMPC: cholesterol: DMPG (± MPLA)

0.9:0.75:0.1 (± 0.2 µg/dose)

[230]

66PyIMP

EPC: cholesterol

2:1

[231]

RTS,S

DOPC: cholesterol: MPLA: QS21^b

1:250:50:50 (w/w)

[204, 223]

PfMSP-1₁₉

SPC: Span 80

86:14 (w/w)

[232]

FMP013

FMP014

DMPC: DMPG: cholesterol: MPLA: QS21^c

6986.27:788.73:5.413:200:100 (w/w)

[233, 234]

Pf25

DPPC: cholesterol: CoPoP: PHAD

4:2:1:1 (w/w)

[235]