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Table 1 Summary of CYP2D6 phenotype and enzymatic activity (activity score)

From: Increased primaquine total dose prevents Plasmodium vivax relapses in patients with impaired CYP2D6 activity: report of three cases

Patient

Allele 1

Allele 2

Activity score

CYP2D6 phenotype

Case 1

*9

*4

0.5

Intermediate metabolizer (gIM)

Case 2

*4

*4

0

Poor metabolizer (gPM)

Case 3

*41

*41

1.0

Normal-slow (gNM-S)

  1. *CYP2D6 allele nomenclature according to PharmVar (https://www.pharmvar.org/gene/cyp2d6)