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Table 2 Surf1.1 nucleotide and amino acid mutation patterns of six different haplotypes identified from Thai isolates

From: Genetic polymorphism of the extracellular region in surface associated interspersed 1.1 gene of Plasmodium falciparum field isolates from Thailand

Haplotype Nucleotide mutation Amino acid mutation Number of isolates Frequency (%)
Haplotype 1 A142G
A145G
G751C
T756C
G795T
A800C
G826C
N48D
I49V
E251Q
I252*
L265F
K267T
E276Q
19 61.3
Haplotype 2 A142G
A145G
G751C
T756C
C863T
N48D
I49V
E251Q
I252*
S288F
5 16.2
Haplotype 3 A684C
C703T
G751C
T756C
C863T
E228D
P235S
E251Q
I252*
S288F
4 12.9
Haplotype 4 T232G
A684C
C703T
G751C
T756C
C863T
Y78D
E228D
P235S
E251Q
I252*
S288F
1 3.2
Haplotype 5 A142G
A145G
G795T
A800C
C863T
N48D
I49V
L265F
K267T
S288F
1 3.2
Haplotype 6 A142G
A145G
G751C
T756C
G795T
G826C
A831G
G840A
G842A
C843T
N48D
I49V
E251Q
I252*
L265F
E276Q
L277*
T280*
T280*
S281N
1 3.2
  1. *Silence mutation