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Table 2 Surf1.1 nucleotide and amino acid mutation patterns of six different haplotypes identified from Thai isolates

From: Genetic polymorphism of the extracellular region in surface associated interspersed 1.1 gene of Plasmodium falciparum field isolates from Thailand

Haplotype

Nucleotide mutation

Amino acid mutation

Number of isolates

Frequency (%)

Haplotype 1

A142G

A145G

G751C

T756C

G795T

A800C

G826C

N48D

I49V

E251Q

I252*

L265F

K267T

E276Q

19

61.3

Haplotype 2

A142G

A145G

G751C

T756C

C863T

N48D

I49V

E251Q

I252*

S288F

5

16.2

Haplotype 3

A684C

C703T

G751C

T756C

C863T

E228D

P235S

E251Q

I252*

S288F

4

12.9

Haplotype 4

T232G

A684C

C703T

G751C

T756C

C863T

Y78D

E228D

P235S

E251Q

I252*

S288F

1

3.2

Haplotype 5

A142G

A145G

G795T

A800C

C863T

N48D

I49V

L265F

K267T

S288F

1

3.2

Haplotype 6

A142G

A145G

G751C

T756C

G795T

G826C

A831G

G840A

G842A

C843T

N48D

I49V

E251Q

I252*

L265F

E276Q

L277*

T280*

T280*

S281N

1

3.2

  1. *Silence mutation