From: The impact of malaria during pregnancy on low birth weight in East-Africa: a topical review
Authors | Country | Study design (year) | Sample size | Treatment; frequency | Method for determining malaria infection | Results/comment |
---|---|---|---|---|---|---|
Kalinjuma et al. [18] | Dar-es-Salaam, Tanzania | Cohort study (2010–2013) | 1115 | SPa; Start in 2nd trimester, then with every ANC visit | Polymerase chain reaction of parasite DNA; quantification of parasites in blood smear; histology of placental tissue | PMb was not significantly associated with LBWc |
Kapisi et al. [4] | Tororo, Uganda | Cohort study (2014) | 282 | SP; Start in 2nd trimester, then given every 8th week | Quantification of parasites in blood smear; histology of placental tissue | Malaria burden during pregnancy—> PM—> risk of LBW (trends, not significant) |
Mohammed et al. [19] | Central Sudan | Case–control study (2010) | 174 | No information given | Polymerase chain reaction of parasite DNA; quantification of parasites in blood smear; histology of placental tissue | Submicroscopic malaria infection during pregnancy—> significantly higher risk of having a LBW delivery |
Dong et al. [20] | Tanzania | Cohort study (2002–2005) | 882 | No information given | Quantification of parasites in blood- and placental smear | CXCL9d was significantly associated with LBW among malaria-infected primigravidae |