Table 1 PfAMA1 peptide allele sets used for PBMC stimulation
Allelic set | Peptides | Sequence | Strain | HLA allele predicted for the 3D7 Pf variant peptide | HLA supertype | Amino acid residue positions |
|---|---|---|---|---|---|---|
1 | e1 | AKDKLFENY | FVO | 278–286 | ||
e2 | AKDKSFQNY | 7G8 | 278–286 | |||
e3 | AKDISFQNY | 3D7 | HLA B*15:03 | B27 | 278–286 | |
2 | e22 | DVYHPINEHR | 7G8, FVO | 36–45 | ||
e23 | DVYRPINEHR | 3D7 | A*68:01 | A03 | 36–45 | |
3 | e24 | EHREHSKEY | 7G8 | 43–51 | ||
e25 | EHREHPKEY | 3D7, FVO | HLA B*15:03 | B27 | 43–51 | |
4 | e46 | DFYKNNEYVK | 7G8, FVO | 200–209 | ||
e48 | HFYKDNKYVK | 3D7 | A*68:01 | A03 | 200–209 | |
5 | e60 | KLFENYTYL | FVO | 282–290 | ||
e61 | KSFQNYTYL | 7G8 | 282–290 | |||
e62 | ISFQNYTYL | 3D7 | A*02:02 B*15:03 B*58:01 | A02 B27 B58 | 282–290 | |
6 | e87 | MTLNGMRDFY | FVO | 193–202 | ||
e88 | MTLDHMRDFY | 7G8 | 193–202 | |||
e89 | MTLDEMRHFY | 3D7 | A*30:02 A*29:02 | A01 A01A24 | 193–202 |