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Table 4 Comparison of Anti-AMA1 IgG subclasses (µg/mL) among different study groups

From: Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children

Group IgG1
Median (Q1–Q3)
IgG2
Median (Q1–Q3)
IgG3
Median (Q1–Q3)
IgG4
Median (Q1–Q3)
Malaria-free controls (n = 200) 3.91 (0.2–35.6) 0.89 (0.1–15.1) 1.1 (0.02–15.4) 0.4 (0.1–1.7)
Uncomplicated malaria (n = 218) 4.23 (0.3–47) 0.73 (0.1–43.6) 3.6 (1–29.6) 0.3 (0.1–3.9)
Severe malaria (n182) 2.97 (0.3–25.7) 3.35 (0.3–45.3) 2 (1–8.5) 1.2 (0.2–14.2)
P value* < 0.001 < 0.001 < 0.001 < 0.001
  1. AMA-1 Apical membrane antigen 1
  2. *P value was derived from Kruskal–wallis between the study groups