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Table 4 Estimates of DNA sequence polymorphism and tests of neutrality at PfEBA-175 region II among global P. falciparum isolates

From: Population genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-175 (EBA-175) gene in Equatorial Guinea

  Sample number S H K Hd + SD π ± SD dn/ds Tajima's D Fu and Li's D Fu and Li's F
Thailand (2006) 48 16 17 6.129 0.895 ± 0.024 0.00437 ± 0.00016 0.004 1.88575 1.20573 1.7012
Thailand (2015) 32 17 24 6.224 0.976 ± 0.015 0.00444 ± 0.00025 0.005 1.33504 0.90921 1.23017
Colombia 20 11 3 3.979 0.568 ± 0.086 0.00284 ± 0.00052 0.004 1.00475 1.43716 1.52132
French Guiana (Maripasoula) 15 10 3 4.114 0.600 ± 0.109 0.00294 ± 0.00053 0.004 1.28567 1.41829 1.58571
Peru 30 9 4 3.425 0.595 ± 0.057 0.00244 ± 0.00022 0.003 1.57791 1.36748 1.67324
Venezuela 9 13 6 5.278 0.889 ± 0.091 0.00377 ± 0.00065 0.005 0.49334 0.67031 0.70214
French Guiana (Camopi) 23 12 4 2.458 0.498 ± 0.111 0.00175 ± 0.00051 0.002 − 0.84514 − 0.6893 − 0.8564
Equatorial Guinea (Bata) 21 17 17 5.762 0.976 ± 0.023 0.00411 ± 0.00028 0.005 0.56395 0.07543 0.25614
Equatorial Guinea (Bioko) 28 23 20 5.704 0.958 ± 0.025 0.00407 ± 0.00035 0.005 − 0.27018 − 0.41803 − 0.4361
Kenya 39 15 21 5.117 0.895 ± 0.037 0.00365 ± 0.00025 0.005 1.13808 1.17499 1.37173
Benin 8 8 7 4.036 0.964 ± 0.077 0.00288 ± 0.00037 0.004 1.48946 1.04971 1.27432
Madagascar 7 11 7 5.762 1.000 ± 0.076 0.00411 ± 0.00056 0.005 0.96043 0.74709 0.8729
Nigeria 30 14 16 4.625 0.816 ± 0.073 0.0033 ± 0.00035 0.004 0.74635 0.75513 0.88276
  1. S: segregating sites, K: average number of pairwise nucleotide differences, H: number of haplotypes, Hd: haplotype diversity, π: observed average pairwise nucleotide diversity, dN: the number of synonymous substitutions per site, dS: the number of nun-synonymous substitutions per site, *P < 0.05