Table 4 Estimates of DNA sequence polymorphism and tests of neutrality at PfEBA-175 region II among global P. falciparum isolates
|  | Sample number | S | H | K | Hd + SD | π ± SD | dn/ds | Tajima's D | Fu and Li's D | Fu and Li's F |
|---|---|---|---|---|---|---|---|---|---|---|
Thailand (2006) | 48 | 16 | 17 | 6.129 | 0.895 ± 0.024 | 0.00437 ± 0.00016 | 0.004 | 1.88575 | 1.20573 | 1.7012 |
Thailand (2015) | 32 | 17 | 24 | 6.224 | 0.976 ± 0.015 | 0.00444 ± 0.00025 | 0.005 | 1.33504 | 0.90921 | 1.23017 |
Colombia | 20 | 11 | 3 | 3.979 | 0.568 ± 0.086 | 0.00284 ± 0.00052 | 0.004 | 1.00475 | 1.43716 | 1.52132 |
French Guiana (Maripasoula) | 15 | 10 | 3 | 4.114 | 0.600 ± 0.109 | 0.00294 ± 0.00053 | 0.004 | 1.28567 | 1.41829 | 1.58571 |
Peru | 30 | 9 | 4 | 3.425 | 0.595 ± 0.057 | 0.00244 ± 0.00022 | 0.003 | 1.57791 | 1.36748 | 1.67324 |
Venezuela | 9 | 13 | 6 | 5.278 | 0.889 ± 0.091 | 0.00377 ± 0.00065 | 0.005 | 0.49334 | 0.67031 | 0.70214 |
French Guiana (Camopi) | 23 | 12 | 4 | 2.458 | 0.498 ± 0.111 | 0.00175 ± 0.00051 | 0.002 | − 0.84514 | − 0.6893 | − 0.8564 |
Equatorial Guinea (Bata) | 21 | 17 | 17 | 5.762 | 0.976 ± 0.023 | 0.00411 ± 0.00028 | 0.005 | 0.56395 | 0.07543 | 0.25614 |
Equatorial Guinea (Bioko) | 28 | 23 | 20 | 5.704 | 0.958 ± 0.025 | 0.00407 ± 0.00035 | 0.005 | − 0.27018 | − 0.41803 | − 0.4361 |
Kenya | 39 | 15 | 21 | 5.117 | 0.895 ± 0.037 | 0.00365 ± 0.00025 | 0.005 | 1.13808 | 1.17499 | 1.37173 |
Benin | 8 | 8 | 7 | 4.036 | 0.964 ± 0.077 | 0.00288 ± 0.00037 | 0.004 | 1.48946 | 1.04971 | 1.27432 |
Madagascar | 7 | 11 | 7 | 5.762 | 1.000 ± 0.076 | 0.00411 ± 0.00056 | 0.005 | 0.96043 | 0.74709 | 0.8729 |
Nigeria | 30 | 14 | 16 | 4.625 | 0.816 ± 0.073 | 0.0033 ± 0.00035 | 0.004 | 0.74635 | 0.75513 | 0.88276 |