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Table 1 Quantitative bias for DBS samples compared to liquid samples

From: Application of dried blood spot sample pooling strategies for Plasmodium 18S rRNA biomarker testing to facilitate identification of infected persons in large-scale epidemiological studies

Sample type

Pf qRT-PCR

Pan qRT-PCR

Bias (log10 parasites/mL blood)

95% limits of agreement

Bias (log10 parasites/mL blood)

95% limits of agreement

Serial dilutions of Pf cultures

− 0.37

− 0.86–0.12

− 0.39

− 0.91–0.14

Venous blood of infected individuals

− 0.21

− 0.73–0.31

− 0.19

− 0.93–0.55

  1. Pf P. falciparum, Pan pan-Plasmodium