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Table 4 Summary of Madagascar and Guinea circumsporozoite (cs) enzyme-linked immunosorbent assay (ELISA) and cs multiplex bead assay (MBA) sporozoite rates for Plasmodium falciparum, P. vivax210 and P. vivax247

From: Adaptation of ELISA detection of Plasmodium falciparum and Plasmodium vivax circumsporozoite proteins in mosquitoes to a multiplex bead-based immunoassay

 

Sporozoite rate % (count) Madagascar

P. falciparum

P. vivax210

P. vivax247

Combined

csELISA

csMBA

csELISA

csMBA

csELISA

csMBA

csELISA

csMBA

Madagascar

n = 1275

 Initial Test

0 (0)

2.4% (31)

1.7% (22)

10.3% (131)

2.1% (27)

3.1% (39)

3.8% (49)

15.8% (201)

 Retest

0 (0)

1.6% (20)

1.3% (17)

6.7% (86)

0.1% (1)

2.0% (25)

1.4% (18)

10.3% (131)

 Boiled Retest

N/A

0 (n = 0)a

N/A

2.1% (27)

N/A

0.7% (9)

N/A

2.8% (36)b

Guinea

n = 255

 Initial Test

2.4% (6)

3.5% (9)

0 (0)

1.2% (3)

0 (0)

0 (0)

2.4% (6)

4.7% (12)

 Retest

2.0% (5)

2.0% (5)

0 (0)

0 (0)

0 (0)

0 (0)

2.0% (5)

2.0% (5)

 Boiled Retest

N/A

2.0% (5)

N/A

0 (0)

N/A

0 (0)

N/A

2.0% (5)

  1. aFor these retests, positive controls failed and results could not be included
  2. bDoes not include boiled retest P. falciparum csMBA sporozoite rate