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Table 3 Paraclinical results according to infecting parasite

From: The clinical–epidemiological profile of malaria patients from Southern Venezuela, a critical hotspot in Latin America

Paraclinical

Total (N = 287; 100%)

P. vivax (N = 200; 69.7%)

P. falciparum (N = 69; 24%)

Mixed malaria (N = 18; 6.3%)

p-value

Haemoglobin (g/dL)

10.99 (1.98)

11.24 (1.67)

10.33 (2.6)

11.12 (1.4)

0.03*†

Alterations (total)

0.041‡

 Mild anaemia (12.9–11)

64 (39.8)

50 (47.2)

11 (25.6)

3 (25)

 

 Moderate anaemia (10.9–7)

68 (42.2)

40 (37.7)

21 (48.8)

7 (58.3)

 

 Severe anaemia (< 7)

6 (3.7)

2 (1.9)

4 (9.3)

–

 

Haematocrit (%)

34 (6)

34.8 (5)

31.9 (8)

34.1 (3.9)

0.02*†

Leukocytes (x mm3)

6,290 (2,800)

6,230 (2,620)

6,390 (3,330)

6,410 (2,460)

0.93*

 Alterations (total)

29 (18)

12 (11.3)

16 (37.2)

1 (8.3)

 < 0.01†||

 Leukopenia (< 4,000/mm3)

17 (10.55)

7 (6.6)

10 (23.26)

–

 

 Leukocytosis (> 10,000/mm3)

12 (7.45)

5 (4.72)

6 (13.95)

1 (8.33)

 

 Neutrophils (%)

47.3 (14.9)

46.3 (14.4)

48.3 (16.4)

50.6 (14.2)

0.52*

 Lymphocytes (%)

47.1 (13.2)

47.6 (13.7)

46.1 (12.4)

46 (12.1)

0.78*

Platelets (x mm3)

89 (48)

88 (38)

90 (56)

93 (83)

0.93*

 Alterations (total)

148 (91.9)

98 (92.5)

39 (90.7)

11 (91.7)

0.58§

 Mild thrombocytopenia (< 150,000/mm3)

40 (24.8)

28 (26.4)

11 (25.6)

1 (8.3)

 

 Moderate thrombocytopenia (< 100,000/mm3)

81 (50.3)

55 (51.9)

18 (41.9)

8 (66.7)

 

 Severe thrombocytopenia (< 50,000/mm3)

27 (16.8)

15 (14.2)

10 (23.3)

2 (16.7)

 

Glycaemia (mg/dL)

79.06 (24.9)

75.24 (22.4)

87.69 (28)

81.8 (27.7)

0.01*†

 Hypoglycaemia (< 60 mg/dL)

39 (24.2)

32 (30.2)

4 (9.3)

3 (25)

0.02§†

 Urea

34.83 (26.2)

33.49 (26)

37.74 (25.8)

36.29 (30.7)

0.64*

 Creatinine (mg/dL)

1.1 (0.8)

0.9 (0.9)

0.96 (0.8)

0.81 (0.3)

0.72*

 Elevation (> 3 mg/dL)

2 (1.2)

1 (0.8)

1 (3.6)

–

0.32‡

 

n = 148 (100%)

n = 99 (66.8%)

n = 39 (26.4%)

n = 10 (6.8%)

 

Total bilirubin [mg/dL]

2.17 [2]

2.45 [2]

2.3 [2]

1.8 [2]

0.39

 Elevation (> 3 mg/dL)

57 (38.5)

40 (40.4)

15 (38.5)

2 (20)

0.45§

 Direct bilirubin [mg/dL]

0.98 [1]

0.96 [1]

1.44 [2]

0.72 [1]

0.14

 Indirect bilirubin [mg/dL]

1.32 [1]

1.42 [1]

1.31 [1]

0.8 [1]

0.39

 

n = 146 (100%)

n = 99 (67.8%)

n = 37 (25.3%)

n = 10 (6.9%)

 

AST (mg/dL)

100 (76)

99 (72)

100 (84)

109 (89)

0.92*

 Elevation (> 35 IU/L)

124 (84.9)

85 (85.9)

31 (83.8)

8 (80)

0.86§

ALT [mg/dL]

77 [127]

94 [161]

51 [82]

37 [152]

0.12

 Elevation (> 45 IU/L)

86 (58.9)

62 (62.6)

21 (56.8)

3 (30)

0.12§

 

n = 144 (100%)

n = 100 (69.4%)

n = 35 (24.3%)

n = 9 (6.3%)

 

LDH (IU/L)

538 (180)

529 (182)

552 (188)

581 (123)

0.61*

 Elevation (> 250 IU/L)

131 (93.6)

91 (92.9)

31 (93.9)

9 (100)

0.52‡

  1. Data for values are expressed as mean (SD–standard deviation–) except for Total, Direct, Indirect bilirubin, and ALT that are expressed as median [IQR –interquartile range–]. Alteration's data are expressed as numbers (percentages). *One-way ANOVA; †Post-hoc analysis: significant difference between P. falciparum and P. vivax (p = 0.019; Tukey); ‡Fisher’s exact test; §Chi-square; ||Post-hoc analysis: only significant for P. falciparum and leukopenia (standardized residue = 2.6); Median’s test
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Malaria Journal

ISSN: 1475-2875

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