Fig. 2

Antigen and population trends measured in dried blood spots (DBS) and serum. (Left) The average seroreactivity in DBS to fragments that were serorecognized in endemic samples was strongly correlated with that in serum (Spearman’s rho 0.8766, p < 0.0001). (Middle) Seroreactivity was higher on average for females in both DBS and serum. Note: points on boxplots are outliers as defined by the Tukey method. (Right) Although overall signal in DBS was lower than in serum, the increase in seroreactivity with age was consistent between the two sample types. Grey shading represents the 95% CI for the regressions. Spearman’s rho 0.5295 (p < 0.0001) and 0.5007 (p < 0.0001) for DBS and serum, respectively