Table 1 Baseline characteristics of study participants according to treatment arm (artemether–lumefantrine vs. artesunate–amodiaquine) at four sites in Mozambique, 2018
Artemether–lumefantrine | Study site | |||
|---|---|---|---|---|
Massinga (N = 95) | Moatize (N = 92) | Montepuez (N = 90) | Mopeia (N = 91) | |
Female gender n (%) | 42 (44.2) | 45 (48.9) | 46 (51.1) | 38 (41.8) |
Age in months (mean ± SD) | 27.8 ± 14.8 | 34.5 ± 15.5 | 24 ± 15.3 | 30.1 ± 12.7 |
Weight in kg (mean ± SD) | 10.7 ± 3.9 | 12.7 ± 3.1 | 9.4 ± 3.7 | 11.1 ± 1.9 |
Fever n (%) | 95 (100) | 92 (100) | 89 (98.9) | 90 (98.9) |
Temperature in °C (mean ± SD) | 38.4 ± 0.9 | 38.8 ± 1 | 38.3 ± 0.8 | 38 ± 0.6 |
Parasite density geometric mean (range) | 24,414.2 (779–184,355) | 43,265.3 (646–192,875) | 46,603.7 (3060–183,724) | 44,131.7 (2201–184,955) |
Hb in g/dl (mean ± SD) | 8.7 ± 1.8 | 10.2 ± 1.5 | 9.1 ± 1.7 | 9.4 ± 1.6 |
Artesunate–amodiaquine | Massinga (N = 92) | Moatize (N = 0) | Montepuez (N = 90) | Mopeia (N = 91) |
|---|---|---|---|---|
Female gender n (%) | 42 (45.7) | NA | 34 (37.8) | 45 (49.5) |
Age in months (mean ± SD) | 30.8 ± 14.4 | NA | 24.8 ± 14.8 | 30.1 ± 13.8 |
Weight in kg (mean ± SD) | 10 ± 5.1 | NA | 10.5 ± 2.5 | 11.8 ± 2.3 |
Fever n (%) | 92 (100) | NA | 89 (98.9) | 91 (100) |
Temperature in °C (mean ± SD) | 38.4 ± 0.9 | NA | 38.4 ± 0.9 | 37.8 ± 0.4 |
Parasite density geometric mean (range) | 32,081.4 (1845–204,526) | NA | 34,703.6 (2757–140,929) | 34,293.9 (2154–173,070) |
Hb in g/dl (mean ± SD) | 8.9 ± 2 | NA | 9.5 ± 1.7 | 9.1 ± 1.4 |