Interaction source | Number of Interactions | Number of proteins | Number of reviewed proteins | Number of pair-wise interactions between reviewed proteins | References |
---|---|---|---|---|---|
A. Functional interactions between annotated Plasmodium falciparum proteins | |||||
 LaCount P. falciparum PPI | 2864 | 1308 | 62 | 17 | [35] |
 Wuchty et al. in silico Plasmodium PPI (1) | 19,979 | 2321 | 85 | 74 | [31] |
 Wuchty et al. experimental PPI (2) | 1428 | 361 | 12 | 11 | [32] |
 Wuchty experimental P. falciparum PPI (3) | 5458 | 1986 | 91 | 32 | [33] |
 Wuchty et al. experimental P. falciparum PPI (4) | 4918 | 1872 | 81 | 15 | [34] |
 IntAct | 2916 | 1343 | 67 | 26 | [28] |
 InterPro | 1013 | 256 | 98 | 241 | [26] |
 Scored BLAST sequence similarity | 1090 (BLAST) | 163 | 130 | 231 | [85] |
 STRING | 617 | 163 | 114 | 386 | [86] |
B. Functional interactions between annotated human proteins | |||||
 Reactome | 79,619 | 8059 | 5029 | 19,736 | [27] |
 Score BLAST sequence similarity | 3,807,888 (BLAST) | 20,395 | 9611 | 143,533 | [85] |
 InterPro | 2,646,550 | 35,928 | 17,797 | 231,799 | [26] |
 Bossi and Lerner | 80,922 | 10,229 | 8416 | 54,238 | [36] |
 STRING | 11,759,454 | 19,354 | 18,836 | 5,244,655 | [86] |
 IntAct | 456,263 | 35,770 | 16,061 | 169,627 | [28] |