Skip to main content

Table 1 Linear Mixed-effects models (LMM). The LMM shows the intraclass correlation coefficient (ICC), the effects of age at the time of vaccination, and the follow-up time effect on the vaccine-induced anti-CSP IgG responses for 7 years

From: Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children

Predictors

RTS,S/AS01-induced anti-CSP IgG Abs

RTS,S/AS01-induced anti-CSP IgM Abs

Naturally-induced anti-CSP IgM Abs (control group)

Coef. (95% CI)

P-value

Coef. (95% CI)

P-value

Coef. (95% CI)

P-value

Time in years (follow-up)

− 0.040 (− 0.051, − 0.043)

 < 0.001

0.004 (0.002, 0.006)

 < 0.001

0.021 (0.010, 0.020)

 < 0.001

Age (5–17 months) at the time of vaccination

− 0.021 (− 0.110, 0.062)

0.602

0.028 (− 0.010, 0.064)

0.143

0.024 (− 0.031, 0.073)

0.47

ICC (δ)

0.28 (3.69)

0.28 (0.68)

0.23 (1.63)

  1. ICC, intraclass correlation coefficient, δ, random effect variances