Skip to main content
Fig. 7 | Malaria Journal

Fig. 7

From: Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes

Fig. 7

Serum ABO blood group does not affect parasite rosetting in vitro. FCR3S1.2 parasites were grown in O RBCs with sera from 20 donors for each blood group for one life cycle. A Rosetting rate and B rosette size were measured by flow cytometry. Pairwise comparison of BgO and all non-O Bgs performed using unpaired t-test with Holm-Bonferroni adjustment of P-values. C, D A antigen levels of RBCs from serum donors were semi-quantified by flow cytometry. Thereafter, the correlation between A-antigen levels and rosetting rate (C) and rosette size (D) was measured and assessed using Spearman’s rank correlation coefficient. All box plots display median values (middle line) and the lower and upper quartile values form the box, with whiskers extending to one and a half times the interquartile range

Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us