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Fig. 2 | Malaria Journal

Fig. 2

From: Preclinical evaluation of strasseriolides A–D, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251

Fig. 2

Compound concentration vs. time graphs of strasseriolides A, C and D used in extrapolating their pharmacokinetic (PK) parameters. For each compound, triplicate mice were injected with I.V. dosage of 25 mg/Kg compound and LC–MS–MS used to quantify compound concentrations in plasma collected at 3-4 different time-points within a 24-hour period. Graphs I, II and III show concentration vs. time relationship for strasseriolides A, C and D respectively

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Malaria Journal

ISSN: 1475-2875

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