Fig. 3

Representation of in vivo mice efficacy after 4 day strasseriolides C and D treatments. Mice were infected with the transgenic P. berghei line 676m1cl1 and treated at 48 h post-infection with 50 mg/kg of strasseriolide C (four replicates, graph A) and 22 mg/kg of strasseriolide D (five replicates, graph B) for 4 days. The vehicle and 20 mg/kg chloroquine were used as controls. The asterisks show significant differences calculated by the Student’s t test. **p < 0.01, ***p < 0.001, vs. the vehicle