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Table 1 Metabolic stability of strasseriolides A–D

From: Preclinical evaluation of strasseriolides AD, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251

  T1/2 Clint Clearance
Strasseriolide (min) (mL/min/mg) Category
A 6.47 ± 1.05 103.28 ± 22.6 High
B 8.7 ± 2.4 76.81 ± 9.8 High
C 15.91 ± 1.15 42.00 ± 1.92 Medium
D >60 >11.13 Low