The association between acute fatty liver disease and nitric oxide during malaria in pregnancy

Malaria Journal

Table 1 Upregulated proteins in the liver of immunized pregnant mice infected with P. berghei NK65

Description	Abbreviation	Uninfected pregnant mouse	Immunized non-pregnant mouse infected with P. berghei NK65	Immunized pregnant mouse infected with P. berghei NK65	Accession
Perilipin-2 OS	Plin2	1.14	0.84	2.13	P43883
Pyruvate kinase PKM OS	Pkm	0.85	1.12	1.73	P52480*
Nicotinamide N-methyltransferase OS	Nnmt	0.52	0.57	1.13	O55239*
Interferon-inducible GTPase 1 OS	Iigp1	1.02	1.24	2.35	Q9QZ85*
Ferritin light chain 1 OS	Ftl1	0.33	1.61	0.79	P29391*
UMP-CMP kinase 2, mitochondrial OS	Cmpk2	1.01	1.02	2.45	Q3U5Q7*
Haptoglobin OS	Hp	1.49	0.82	4.09	Q61646*
Thymosin beta-10 OS	Tmsb10	0.63	3.58	1.82	Q6ZWY8*
Histone H2A type 1-H OS	Hist1h2ah	0.17	0.56	0.54	Q8CGP6*
Hemopexin OS	Hpx	0.85	0.88	2.67	Q91X72*
Signal transducer and activator of transcription 1 OS	Stat1	0.89	1.35	2.93	P42225*
Z-DNA-binding protein 1 OS	Zbp1	1.16	1.30	3.91	Q9QY24*
Coronin-1A OS	Coro1a	0.58	1.28	2.03	O89053*
Metallothionein-2 OS	Mt2	2.17	0.22	8.34	P02798*
Metallothionein-1 OS	Mt1	1.38	0.61	6.02	P02802*
Interferon-induced very large GTPase 1 OS	Gvin1	0.79	1.66	4.84	Q80SU7*
Interferon-induced protein with tetratricopeptide repeats 3 OS	Ifit3	0.54	1.41	9.25	Q64345*
Serum amyloid A-1 protein OS	Saa1	0.72	0.71	16.41	P05366*

Protein levels in the livers of immunized pregnant mice infected with P. berghei NK65 were compared with the levels in uninfected non-pregnant mice. Proteins with at least three peptide spectral matches and a fold change > 2.0 compared with unimmunized non-pregnant mice without infection (naïve virgin mice) are listed. Asterisks indicate proteins with significantly higher levels than in unimmunized non-pregnant mice without infection (naïve virgin mice) (> twofold change). Additional file 1: Table S1 shows all proteins detected in this study. Data are representative of three independent experiments

ISSN: 1475-2875