Skip to main content

Table 3 Frequency of haplotypes over time

From: Temporal evolution of the resistance genotypes of Plasmodium falciparum in isolates from Equatorial Guinea during 20 years (1999 to 2019)

Year

(N)

Partially resistant

(IRNG)

Fully resistant

(IRNGE)

Super resistant

(IRNGEG)

N (Freq.)

95% CI

N (Freq.)

95% CI

N (Freq.)

95% CI

1999

(60)

26 (43.3%)

31.57–55.9

5 (8.3%)

3.61–18.07

0

0–6.02

2001

(102)

44 (43.1%)

33.95–52.83

0

0–3.63

0

0–3.63

2004/5

(262)

149 (56.8%)

50.8–62.9

10 (3.9%)

2.09–6.88

1 (0.39%)

7e-02–2.13

2006

(158)

99 (62.6%)

54.9–69.8

3 (1.89%)

0.65–5.43

0

0–2.37

2011

(163)

130 (79.75%)

72.93–85.21

6 (3.7%)

1.70–7.80

0

0–2.3

2013

(170)

145 (85.2%)

79.19–89.84

19 (11.2%)

7.27–16.8

1 (0.6%)

0.10–3.26

2016

(169)

137 (81.1%)

74.49–86.26

20 (11.8%)

7.79–17.57

3 (1.7%)

0.61–5.09

2019

(139)

120 (86.3%)

79.64–91.07

42 (30.2%)

23.20–38.30

0

0–2.69

p-value

0

 

0

 

0.161

 
  1. ≤ 0.05 is taken as significance value. N: number of samples analysed
  2. The frequency of each of the three haplotypes into which they have been classified: partially resistant 51I/59R/108 N/437G (IRNG), fully resistant 51I/59R/108N/437G/540E (IRNGE) and super resistant 51I/59R/108N/437G/540E/581G (IRNGEG)