Investigating molecular mechanisms of insecticide resistance in the Eastern Democratic Republic of the Congo

Malaria Journal

Table 6 An. funestus s.l. metabolic allele frequencies from two study sites in East DRC

Resistance mutation	Study site	# Mosquitoes tested^a	Homozygote mutation (RR)	Heterozygote mutation (RS)	Homozygote wild type (SS)	Allele frequency		χ² test	p-value
Resistance mutation	Study site	# Mosquitoes tested^a	Homozygote mutation (RR)	Heterozygote mutation (RS)	Homozygote wild type (SS)	R	S	χ² test	p-value
L119F-GSTe2	Tchonka	126	0	0	126	0	1.0	–	–
L119F-GSTe2	Tushunguti	27	0	0	27	0	1.0	–	–
CYP6P9a	Tchonka	131	83	48	0	0.82	0.18	6.59	0.01
CYP6P9a	Tushunguti	21	20	1	0	0.98	0.02	0.01	0.91
CYP6P9b	Tchonka	121	83	35	3	0.83	0.17	0.09	0.76
CYP6P9b	Tushunguti	17	9	4	4	0.65	0.35	4.0	0.05

ISSN: 1475-2875