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Table 3 Correlations between parasite parameters and haemoglobin variables in P. falciparum and P. vivax in those who did not recrudesce

From: Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria

Correlation Pf3D7 (n = 170) P. vivax (n = 39)
  r-value Unadjusted P-value a Adjusted P-value b r-value Unadjusted P-value a Adjusted P-value c
PPPre and Haemoglobin nadir 0.06 0.44 0.82 − 0.47 0.002 0.001
PPPre and Fractional Fall of Haemoglobin − 0.05 0.49 0.43 0.32 0.045 0.041
TPBPre and Haemoglobin nadir 0.07 0.39 0.99 − 0.57 0.0001 0.002
TPBPre and Fractional Fall of Haemoglobin − 0.01 0.89 0.78 0.39 0.013 0.040
  1. n number of participants, TPBPre pre-treatment total parasite burden, PPPre Pre-treatment peak parasitaemia
  2. aPearson’s correlation (with PPPre and TBP log10 transformed); badjusted for drugs by including drug as an explanatory variable in a linear regression model; cadjusted for drugs and by day of treatment by including drug and day of treatment as explanatory variables in a linear regression model