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Table 2 Number of clinical malaria cases, incidence rates and incidence rate ratios (IRR) of the follow-up study

From: Incidence of clinical malaria, acute respiratory illness, and diarrhoea in children in southern Malawi: a prospective cohort study

 

Total child-years in the study

Total child-years at riska

Children with at least one clinical malaria case: n (%)

Clinical malaria cases

Incidence rate: per child-years at risk (95% CI)

IRR (95% CI)

Overall

235.7

231.5

96 (35.0%)

110

0.5 (0.4–0.5)

–

Focal area

 A

105.0

103.7

29 (27.6%)

34

0.3 (0.2–0.4)

Reference

 B

57.6

55.5

53 (67.9%)

56

1.0

3.3 (1.2–5.1)

 C

73.0

72.2

14 (15.2%)

20

0.3 (0.2–0.4)

1.0 (0.6–1.7)

Intervention arm

 Control

69.5

68.5

21 (25.6%)

26

0.4 (0.3–0.5)

Reference

 HI

58.6

58.3

5 (8.2%)

7

0.1 (0.1–0.2)

0.3 (0.1–0.7)

 LSM

67.1

65.4

43 (52.4%)

44

0.7 (0.6–0.8)

1.8 (1.1–2.9)

 HI & LSM

40.4

39.1

27 (55.1%)

33

0.8 (0.7–1.0)

2.0 (1.2–3.3)

Age in months

 6.0–11.9

44.9

44.8

2 (4.0%)

2

0.04 (0.01–0.2)

Reference

 12.0–23.9

77.9

76.3

33 (38.8%)

41

0.5 (0.4–0.7)

12.5 (3.0–51.7)

 24.0–59.9

112.8

110.2

61 (43.9%)

67

0.6 (0.5–0.7)

15.0 (3.7–61.2)

  1. Reference for all calculations including IRR is from Rothman et al. [29]
  2. The reference or comparison area/intervention arm/age-group have been labelled as Reference
  3. aCalculated from subtracting 14 days from total child-years for each malaria case; child-years at risk also includes the period of follow-up of children who did not complete 12 months