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Table 1 Parameters varied during the simulation analyses

From: How radical is radical cure? Site-specific biases in clinical trials underestimate the effect of radical cure on Plasmodium vivax hypnozoites

Variance in mosquito biting

Time to relapse (d)

Follow-up (d)

Prophylaxis (d)

Effect of transmission intensity and heterogeneity in biting

0, 1, 2, 3

65

180

28

Effect of rate of relapse and duration of follow-up

0

30, 60, 90, 180

90, 180, 365, 730

28

Effect of vector control/genotyping/efficacy metric and infection endpoint

0

65

180

28

Effect of the 8-aminoquinoline

0

65

180

28, 45

  1. The parameters that were varied during each simulation analysis are reported. All other parameters in the transmission model are set to default values and are consistent with the values reported in Additional file 1: Tables S1 and S2