Table 1 Ingredients and proportions of each component in preparation of DQ liposome formulation
From: Decoquinate liposomes: highly effective clearance of Plasmodium parasites causing severe malaria
Formulation | SPC (mg) | DQ (mg) | Chol (mg) | P188 (mg) | PEG 400 (mg) | EtOH (ml) | H2O (ml) | Other (mg) |
|---|---|---|---|---|---|---|---|---|
F1 | 80 | 20 | – | – | – | 15 | 285 | – |
F2 | 40 | 20 | 10 | – | – | 30 | 270 | – |
F3 | 80 | 40 | 20 | – | 65 | 30 | 270 | – |
F4 | 80 | 40 | 7 | 60 | 102 | 15 | 285 | – |
F5 | 80 | 20 | – | 160 | 65 | 15 | 285 | – |
F6 | – | 20 | – | 160 | 65 | 15 | 285 | 80 (EPC) |
F7 | – | 20 | – | 160 | 65 | 15 | 285 | 80 (HSPC) |
F8 | 80 | 40 | – | – | – | 30 | 270 | 130 (HS15) |