Table 3 Physicochemical property evaluations of DQ liposomes in 0 and 5 days after preparation (n = 3)
From: Decoquinate liposomes: highly effective clearance of Plasmodium parasites causing severe malaria
Measurements | Days | Samples | |||
|---|---|---|---|---|---|
F1 | F2 | F5 | F8 | ||
PS (nm) | 0 | 141.5 ± 0.3 | 124.7 ± 1.3 | 133.1 ± 1.4 | 144.1 ± 4.0 |
5 | 146.9 ± 2.6 | 153.3 ± 1.1 | 149.8 ± 0.4 | 153.6 ± 0.6 | |
PDI | 0 | 0.266 | 0.200 | 0.269 | 0.213 |
5 | 0.259 | 0.194 | 0.271 | 0.234 | |
Zeta potential (mV) | 0 | 0.90 ± 0.17 | 2.21 ± 0.62 | − 17.4 ± 0.59 | − 6.59 ± 0.33 |
5 | 1.11 ± 0.11 | 5.31 ± 0.34 | − 19.9 ± 0.76 | − 9.76 ± 0.47 | |
EE (%) | 0 | 98.8 ± 2.0 | 96.3 ± 2.2 | 98.7 ± 1.8 | 99.2 ± 3.0 |
5 | 99.3 ± 2.4 | 95.9 ± 1.6 | 99.6 ± 1.6 | 99.8 ± 2.4 | |