Table 3 Secondary efficacy outcomes of children with uncomplicated malaria after 28 days of follow up

Early treatment failure

98/182 (53.8%)

1/171 (0.6%)

Late treatment failure

26 (14.3%)

36 (21.1%)

 Due to recrudescence

4

4

 Due to a new infection

22

32

Proportion of parasitaemic children

 Day 2

141/188 (75.0%)

21/189 (11.1%)

 Day 3

94/187 (50.3%)

1/188 (0.5%)

Number of children with gametocytes who had no gametocytes on Day 0

 Day 7

10

1

 Day 14

6

0

 Day 21

3

0

 Day 28

0

1

Mean Hb (g/dl) on day 28 (SD)

10.96 (1.47)

10.68 (1.30)

Mean increase in Hb on Day 28 (SE)[N]

1.12 (0.24) [N = 67]

0.84 (0.17) [N = 150]

Anaemia prevalence (Hb < 11 g/dl) on day 28 (%)

26/67 (38.8%)

68/150 (45.3%)