Table 4 Haematological and biochemical assessments
| Â | Quinine plus clindamycin | Artemether-lumefantrine | P-value | ||
|---|---|---|---|---|---|
| Â | No. tested | Mean (SD) | No. tested | Mean (SD) | |
White blood cell count (109/L) | |||||
 Day 0 | 132 | 9.31 (4.2) | 134 | 10.10 (7.8) | 0.311 |
 Day 28 | 51 | 7.92 (3.3) | 118 | 7.71 (3.3) | 0.701 |
 P value | 0.035 | 0.002 |  | ||
Lymphocyte count (%) | |||||
 Day 0 | 131 | 30.06 (12.7) | 133 | 34.5 (42.1) | 0.252 |
 Day 28 | 50 | 45.2 (14.7) | 118 | 47.4 (13.5) | 0.345 |
|  |  < 0.0001 | 0.0016 |  | ||
Red blood cell count (1012/L) | |||||
 Day 0 | 132 | 4.38 (4.3) | 133 | 3.93 (1.00) | 0.451 |
 Day 28 | 51 | 4.56 (1.05) | 118 | 4.39 (0.90) | 0.275 |
| Â | 0.768 | 0.0002 | Â | ||
Haemoglobin concentration (g/dl) | |||||
 Day 0 | 131 | 9.64 (1.8) | 133 | 9.8 (1.6) | 0.425 |
 Day 28 | 51 | 10.9 (1.5) | 118 | 10.6 (1.2) | 0.070 |
|  |  < 0.0001 |  < 0.0001 |  | ||
Alkaline phosphatase concentration (U/L) | |||||
Day 0 | 164 | 21.1 (14.7) | 164 | 20.5 (18.5) | 0.738 |
Day 28 | 58 | 17.7 (8.7) | 129 | 17.7 (7.7) | 0.997 |
| Â | 0.098 | 0.108 | Â | ||
Creatinine concentration (µmol/L) | |||||
 Day 0 | 164 | 44.3 (16.5) | 164 | 46.5 (31.9) | 0.432 |
 Day 28 | 58 | 49.2 (16.6) | 129 | 46.1 (15.2) | 0.219 |
| Â | 0.054 | 0.896 | Â | ||