Table 4 Approaches of pfhrp2 gene deletion analysis against the WHO guideline for its investigation
Author | Study design | Participants | Sample size | Type of samples | Pf Confirmation | Methods of pfhrp2 gene deletion detection |
|---|---|---|---|---|---|---|
WHO guideline | Cross sectional | Symptomatic | 370 | RDT − and Microscopy + or RDT − and Pf-pLDH RDT + | PCR | PCR |
Koitaa et al. [16] | Retrospective | Symptomatic | 480 | HRP2 RDT − and Microscopy + | PCR | PCR |
Wurtzb et al. [38] | Cross sectional | Symptomatic | 122 | HRP2 RDT − and Microscopy + | PCR | PCR |
Parra et al. [36] | Cross sectional | Asymptomatic | 783 | RDT −/PCR + | PCR | PCR |
Amoahb et al. [39] | Cross sectional | Healthy children | 94 | RDT −/PCR + | PCR | PCR |
Menegonb et al. [40] | Cross sectional | Symptomatic | 144 | Microscopy + /PCR + | PCR | PCR |
Kozyckib et al. [41] | Cross sectional | Symptomatic | 156 | RDT − and Microscopy + | PCR | PCR |
Beshirb et al. [19] | Cross sectional | Asymptomatic | 106 | PCR + | PCR | PCR |
Guptab et al. [42] | Cross sectional | All population | 69 | RDT − and Microscopy + | PCR | PCR |
Berhanieb et al. [22] | Cross sectional | Symptomatic | 50 | RDT − and Microscopy + | PCR | PCR |
Kobayashib et al. [43] | Retrospective | Asymptomatic | 36 | RDT − and Microscopy + | PCR | PCR |
Funweib et al. [44] | Not specified | Symptomatic | 66 | RDT − and Microscopy + | PCR | PCR |
Iriartb et al. [30] | Cross sectional | Symptomatic | 79 | RDT −/PCR + | PCR | PCR |
Boscob et al. [46] | Cross sectional | Symptomatic | 195 | RDT −/PCR + | PCR | PCR |
Prosserb et al. [47] | Retrospective | Symptomatic | 210 | PCR + | PCR | PCR |
Alemayehub et al. [48] | Cross sectional | Symptomatic | 218 | PCR + | PCR | PCR |
Patia et al. [49] | Cross sectional | Symptomatic | 384 | RDT −/PCR + | PCR | PCR |
Bhartib et al. [50] | Cross sectional | Symptomatic | 1521 | PCR + | PCR | PCR |
Kumarb et al. [17] | Cross sectional | Symptomatic | 48 | Microscopy +/PCR + | PCR | PCR |
Viana et al. [51] | Cross sectional | Symptomatic | 223 | Microscopy +/PCR + | PCR | PCR |
Gamboab et al. [13] | Retrospective | Symptomatic | 148 | Microscopy + | PCR | PCR |
Goesb et al. [52] | Retrospective | Symptomatic | 159 | Microscopy +/PCR + | PCR | PCR |
Akinyib et al. [53] | Retrospective | Symptomatic | 188 | Microscopy +/PCR + | PCR | PCR |
Solanob et al. [12] | Retrospective | Symptomatic | 100 | Not clear | PCR | PCR |
Fontechab et al. [54] | Cross sectional | Symptomatic | 128 | Microscopy +/PCR + | PCR | PCR |