Table 1 The plasma pharmacokinetic parameters of SPQ and RPQ in mice
From: Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice
SPQ | RPQ | |
|---|---|---|
Lag time (h) | 0 | 0 |
Cmax (µg/mL) | 1.05 ± 0.15 | 0.72 ± 0.11 |
Tmax (h) | 1 | 0.5 |
Tlast (h) | 8 | 2 |
AUC0-last (µg h/mL) | 1.58 | 0.64 |
T1/2 (h) | 1.9 | 0.45 |