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Fig. 2 | Malaria Journal

Fig. 2

From: Similarly efficacious anti-malarial drugs SJ733 and pyronaridine differ in their ability to remove circulating parasites in mice

Fig. 2

SJ733 rapidly removes blood-stage parasites from circulation. A Schematic showing C57BL/6 J mice (n = 6/group) administered CTFR+ RBC harbouring P. berghei-GFP (termed Gen0), treated immediately with control saline, sodium artesunate or SJ733, and peripheral blood monitored individually at times indicated by flow cytometry to monitor Gen0 pRBC and emergence of Gen1+ pRBC. B Flow cytometric gating strategy for identifying Gen0 and Gen1+ pRBC and assessing parasite life-stages. C Representative FACS plots for total RBC over time, showing the dynamics of Gen0 and Gen1+ pRBC. D Summary of Gen0 and Gen1+ pRBC dynamics expressed as a percentage of total RBC. Error bars represent the standard the standard error of the mean

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