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Table 3 RDT accuracy for detecting pLDH and HRP2 antigens compared to bead-based assay

From: Investigation of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions and performance of a rapid diagnostic test for identifying asymptomatic malaria infection in northern Ethiopia, 2015

  

pLDH RDT band

HRP2 RDT band

Sensitivity

% (95% CI)

n/N

53.8 (25.1–80.8)

7/13

53.3 (34.3–71.7)

16/30

Specificity

% (95% CI)

n/N

99.6 (99.3–99.8)

2624/2635

99.7 (99.3–99.8)

2609/2618

PPV

% (95% CI)

38.9 (17.3–64.3)

64.0 (42.5–82.0)

NPV

% (95% CI)

99.8 (99.5–99.9)

99.5 (99.1–99.7)

Kappa coefficient

% (95% CI)

0.45 (0.23–0.67)

0.58 (0.42–0.73)

  1. CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value
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Malaria Journal

ISSN: 1475-2875

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