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Table 1 Pre-treatment characteristics of the study participants

From: A single low dose of primaquine is safe and sufficient to reduce transmission of Plasmodium falciparum gametocytes regardless of cytochrome P450 2D6 enzyme activity in Bagamoyo district, Tanzania

Variable estimate

 

Male sex, n (%)

87 (55.4)

Age (years), median (Interquartile range)

6.4 (4.0–8.2)

Weight (kg), mean (SD)

18.9 (5.5)

Axillary temperature (°C), mean (SD)

38.1 (1.2)

Febrile (≥ 37.5 °C), n (%)

109 (69.4)

Hb (g/dL), mean (SD)

10.8 (1.4)

CYP2D6 reduced Hb (g/dL), mean (95%CI)

11.3 (10.8–11.7)

CYP2D6 normal Hb (g/dL), mean (95%CI)

10.6 (10.4–10.9)

CYP2D6 increased Hb (g/dL), mean (95%CI)

11.3 (6.9–15.7)

G6PD deficient Hb (g/dL), mean (95%CI)

10.8 (9.8–11.7)

G6PD normal Hb (g/dL), mean (95%CI)

10.8 (10.5–11.0)

Heterozygous female, Hb (g/dL), mean (95%CI)

10.8 (10.2–11.2)

Anaemic (Hb < 11.0 g/dL), n (%)

85 (54.1)

Asexual parasite density by microscopy/μL, geometric mean (SD)

16,571 (4.9)

Hemizygous/homozygous G6PD deficient, n (%)

20 (12.7)

G6PD heterozygous female, n (%)

21 (13.4)

CYP2D6 reduced activity, n (%)

33 (21.0)

CYP2D6 increased activity, n (%)

3 (1.9)

  1. Hb haemoglobin, SD standard deviation, CI confidence interval