Quantification of the dynamics of antibody response to malaria to inform sero-surveillance in pregnant women

Malaria Journal

Table 4 Performance of classifying controls to Cluster 1^a and cases to Cluster 2^b based on univariate analyses^c

	Number of controls^d classified into Cluster 1 (%)	Number of cases^e classified into Cluster 2 (%)	Total women classified into the expected Cluster^f (%)
PfAMA1	76 (66.1)	74 (54.8)	150 (60)
PfVAR2CSA	86 (74.8)	57 (42.2)	143 (57.2)
PfEBA175	61 (53.0)	81 (60.0)	142 (56.8)
PvAMA1	109 (94.8)	28 (20.7)	137 (54.8)
PfMSP3	103 (89.6)	33 (24.4)	136 (54.4)
PfMSP2	63 (54.8)	67 (49.6)	130 (52)

^aCluster 1 (low immunity group)
^bCluster 2 (high immunity group)
^cAntibodies are ordered from the highest to the lowest percentage of classifying pregnant women into the expected cluster
^dOut of 115 controls
^eOut of 135 cases
fComputed based on the decision made that Cluster 1 would represent controls and Cluster 2 would represent cases. The sum of controls classified into Cluster 1 and cases classified into Cluster 2 were then divided by the total pregnant women, i.e. 250 to obtain the percentage

ISSN: 1475-2875