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Table 4 Prevalence of Pfdhfr, Pfdhps, among pregnant women in study isolates

From: Intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine and parasite resistance: cross-sectional surveys from antenatal care visit and delivery in rural Ghana

Gene

SNP*

Wild type, n (%)

Mutation, n (%)

Pfdhfra (n = 112)

N51I

12 (10.71%)

100 (89.29%)

 

C59R

3 (2.68%)

109 (97.32%)

 

S108N

2 (1.79%)

110 (98.21%)

 

I164L

111 (99.11%)

1 (0.89%)

Pfdhpsb (n = 105)

S436A/F

29 (27.62%)

76 (72.38%)

 

A437G

3 (2.86%)

102 (97.14%)

 

K540E

105 (100%)

0

 

A581G

82 (78.10%)

22 (20.90%)

 

A613S/T

100 (95.24%)

5 (4.76%)

  1. a Pfdhfr, dihydrofolate reductase; b Pfdhps, dihydropteroate synthase