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Table 3 Risk and protective factors associated with P. knowlesi infection and exposure

From: Plasmodium knowlesi: the game changer for malaria eradication

Categories

Risk/protective

Factors

Source

Individual

Risk

Age

[62, 63, 69, 70, 75, 79]

Male

Race

Direct contact with monkeys

Forest-related and/or agricultural work (farmer, oil palm plantation worker, and vegetation clearing)

Travel into the forests/ eco-tourism

Sleep outside the house

Stay overnight in forest or in workplace near forest

Previous malaria infection

Lack of usage of personal protection (bed net, repellent/ residual insecticide spray)

Protective

G6PD deficiency

[62, 70]

Personal protection (bed net, repellent/ residual insecticide spray)

Lived in village

Environmental

Risk

Areas with significant forest coverage (within 2 km radius)

[62, 80, 81]

Rapid deforestation (within 2 km radius)

Oil palm plantation and fragmentation of oil palm plantations

Patches of dense forest/ fragmentation of forests

Presence of wild monkeys

Long grass around house

Open roof eaves/gaps in house walls

Protective

Altitude elevation

[62, 80]

Rice paddy fields around house