Table 5 Pfcrt and Pfmdr-1 mutation and alleles observed in P. falciparum obtained from blood samples collected prior antimalarial treatment
Bensonville | Saclepea | Kakata | Sinje | Total | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | n | % | N | % | ||
Mutation | Pfcrt | ||||||||||
76 T | 29 | 85.3 | 19 | 90.5 | 20 | 95.2 | 12 | 80.0 | 80 | 87.9 | |
Pfmdr-1 | |||||||||||
86Y | 16 | 47.1 | 8 | 38.1 | 12 | 57.1 | 4 | 26.7 | 40 | 44.0 | |
184F | 16 | 47.1 | 10 | 47.6 | 11 | 52.4 | 10 | 66.7 | 47 | 51.6 | |
Alleles | Pfcrt | ||||||||||
WT | 5 | 14.7 | 2 | 9.5 | 1 | 4.8 | 3 | 20.0 | 11 | 12.1 | |
74I/75E/76 T | 11 | 32.4 | 8 | 38.1 | 6 | 28.6 | 4 | 26.7 | 29 | 31.9 | |
74I/75E/76 T/362 V | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 1 | 6.7 | 1 | 1.1 | |
74I/75E/76 T/356 T | 16 | 47.1 | 8 | 38.1 | 10 | 47.6 | 6 | 40.0 | 40 | 44.0 | |
74I/75E/76 T/217F/356 T | 0 | 0.0 | 1 | 4.8 | 0 | 0.0 | 0 | 0.0 | 1 | 1.1 | |
74I/75E/76 T/141L | 0 | 0.0 | 1 | 4.8 | 2 | 9.5 | 0 | 0.0 | 3 | 3.3 | |
74I/75E/76 T/141L/356 T | 2 | 5.9 | 1 | 4.8 | 2 | 9.5 | 1 | 6.7 | 6 | 6.6 | |
Total | 34 | 100.00 | 21 | 100.00 | 21 | 100.00 | 15 | 100.00 | 91 | 100.00 | |
Pfmdr-1 | |||||||||||
WT | 9 | 26.5 | 5 | 23.8 | 5 | 23.8 | 2 | 13.3 | 21 | 23.1 | |
86Y | 6 | 17.6 | 5 | 23.8 | 5 | 23.8 | 1 | 6.7 | 17 | 18.7 | |
184F | 9 | 26.5 | 8 | 38.1 | 4 | 19.0 | 9 | 60.0 | 30 | 33.0 | |
86Y/1246Y | 3 | 8.8 | 1 | 4.8 | 0 | 0.0 | 2 | 13.3 | 6 | 6.6 | |
86Y/184F | 6 | 17.6 | 2 | 9.5 | 7 | 33.3 | 1 | 6.7 | 16 | 17.6 | |
86Y/184F/1276Y | 1 | 2.9 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 1 | 1.1 | |
Total | 34 | 100.00 | 21 | 100.00 | 21 | 100.00 | 15 | 100.00 | 91 | 100.00 | |