Fig. 3From: A single point mutation in the Plasmodium falciparum 3′–5′ exonuclease does not alter piperaquine susceptibilityAnalysis of growth rates. P. falciparum parasites with PfEXO wild-type (W2, 3D7 and B5), PfEXO-E415G transgenic line (B5-rexo-E415G-B8), and clinical isolates with the combination of PfEXO-E415G and multiple pfpm2 copies (ASAP-21 and ASAP-168) were synchronized (initiated at 0.1% parasitaemia ring stage, 2% haematocrit) and followed for 168 hours. Nucleic acids were stained with SYBR Green I and parasitaemia assessed by flow cytometry. Raw values were corrected, and data represent mean ± S.D. from 3 independent experimentsBack to article page