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Table 2 Piperaquine (PPQ) susceptibility (mean ± SD)

From: A single point mutation in the Plasmodium falciparum 3′–5′ exonuclease does not alter piperaquine susceptibility

Sample

PPQ-IC50 (nM)

PPQ-IC90 (nM)

B5

112 ± 54

172 ± 9

B5-rexo-E415G-B8

185 ± 541

243 ± 221

ASAP-21

5207 ± 6902

 N.D.

ASAP-168

111 ± 171

312 ± 371

  1. 1No significant difference (P value > 0.05) compared to B5 as tested by Mann–Whitney U Test
  2. 2Significant difference (P value = 0.0167) between ASAP-21 and B5 as tested by Mann–Whitney U Test
  3. N.D. for not determined