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Table 1 Epidemiological clinical parameters for uncomplicated and severe P. vivax malaria patients from Manaus, Amazonas state

From: Duffy blood system and G6PD genetic variants in vivax malaria patients from Manaus, Amazonas, Brazil

Clinical Signs

Female

Male

Severe

(n = 60)

Uncomplicated

(n = 47)

p-value

Severe

(n = 68)

Uncomplicated

(n = 50)

p-value

Abdomen pain

43

35

NS

44

33

NS

Severe anaemia

13

1

.002 *

11

1

 < .001 *

Loss of appetite

51

35

NS

5

37

NS

Choluria

44

23

.008 **

53

21

 < .001 *

Cough

24

16

NS

21

16

NS

Diarrhea

17

12

NS

28

18

NS

Dyspnea

20

23

NS

24

18

NS

Epistaxis

3

5

NS

3

10

.008 *

Headache

56

39

NS

51

46

.013 **

Hemoglobinuria

11

6

NS

14

3

.021 *

Hepatosplenomegaly

39

20

.016 *

49

14

 < .001 **

Jaundice

43

9

 < .001 **

43

12

 < .001 **

Leukocyturia

20

18

NS

30

8

 < .001 **

Obesity

5

5

NS

9

1

.028 *

Oliguria

09

4

NS

10

4

NS

Pallor

50

33

NS

56

43

NS

Petechia

3

11

.005 *

3

5

NS

Vomiting

50

40

NS

44

36

NS

Whole blood transfusion

10

4

NS

18

3

 < .001 *

  1. It show little difference in clinical signs between genders when diagnosed with uncomplicated and severe vivax malaria. However, male patients most frequently report symptoms when they have severe malaria
  2. N: Cases. Results are based on * χ2 test (Yates’s corrections) and ** Fisher Exact Test. NS: no statistically significant association (P > 0.05). Statistically significant associations (P < 0.05) are emphasized in bold type