From: Duffy blood system and G6PD genetic variants in vivax malaria patients from Manaus, Amazonas, Brazil
Clinical Signs | Female | Male | ||||
---|---|---|---|---|---|---|
Severe (n = 60) | Uncomplicated (n = 47) | p-value | Severe (n = 68) | Uncomplicated (n = 50) | p-value | |
Abdomen pain | 43 | 35 | NS | 44 | 33 | NS |
Severe anaemia | 13 | 1 | .002 * | 11 | 1 |  < .001 * |
Loss of appetite | 51 | 35 | NS | 5 | 37 | NS |
Choluria | 44 | 23 | .008 ** | 53 | 21 |  < .001 * |
Cough | 24 | 16 | NS | 21 | 16 | NS |
Diarrhea | 17 | 12 | NS | 28 | 18 | NS |
Dyspnea | 20 | 23 | NS | 24 | 18 | NS |
Epistaxis | 3 | 5 | NS | 3 | 10 | .008 * |
Headache | 56 | 39 | NS | 51 | 46 | .013 ** |
Hemoglobinuria | 11 | 6 | NS | 14 | 3 | .021 * |
Hepatosplenomegaly | 39 | 20 | .016 * | 49 | 14 |  < .001 ** |
Jaundice | 43 | 9 |  < .001 ** | 43 | 12 |  < .001 ** |
Leukocyturia | 20 | 18 | NS | 30 | 8 |  < .001 ** |
Obesity | 5 | 5 | NS | 9 | 1 | .028 * |
Oliguria | 09 | 4 | NS | 10 | 4 | NS |
Pallor | 50 | 33 | NS | 56 | 43 | NS |
Petechia | 3 | 11 | .005 * | 3 | 5 | NS |
Vomiting | 50 | 40 | NS | 44 | 36 | NS |
Whole blood transfusion | 10 | 4 | NS | 18 | 3 |  < .001 * |