Fig. 2

Phanerozoites of Plasmodium (Haemamoeba) matutinum in endothelial cells of brain (a–f), eye (h, i), lungs (j), pectoral muscle (k) and kidney (l). Two phanerozoites in different stages of maturation in a capillary of the frontal telencephalon (a); note that the younger phanerozoite (top) contains more vacuoles, larger nuclei and more cytoplasm than the nearly mature phanerozoite (bottom). Maturing phanerozoite in a capillary of the frontal telencephalon (b); note that the parasite completely blocks the capillary. Four phanerozoites at different stages of maturation in capillary endothelial cells of the frontal telencephalon (c); note the signs of cellular disintegration and nuclear fragmentation, whose exclusive occurrence in close neighbourhood to phanerozoites supports vascular blockage as cause of disintegration. Two phanerozoites in different stages of maturation in capillary endothelial cells of the molecular layer of the cerebellum (d); congestion of erythrocytes is visible. Maturing phanerozoite in a capillary endothelial cell of the mesencephalon (e). Mature phanerozoite in the frontal telencephalon (f); note that vacuolization is still visible in the maturing parasite. Fibrinoid microthrombosis in a capillary of the cerebellum molecular layer (g). Phanerozoite in a capillary endothelial cell of the endomysium of an oculomotoric skeletal muscle fibre, which is adjacent to the ocular bulb (h). Phanerozoite within a capillary endothelial cell of the Pecten oculi (i). Phanerozoite in capillaries of lung (j) and pectoral muscle (k); note the closely located nuclei of host cells. Phanerozoite in the kidney (l); note the markedly vacuolated cytoplasm. Images taken from cytologic imprints in Wright-Giemsa stain (a–c, f, l) and histologic preparations in hematoxylin & eosin stain (d, e, g–k). Simple arrows vacuoles, triangle arrowhead nuclei of developing phanerozoites, triangle wide arrowheads host cell nuclei, simple wide arrows developing merozoites, triangle arrow microthrombus Scale bars 10 μm