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Fig. 1 | Malaria Journal

Fig. 1

From: Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside

Fig. 1

A Scheme of infection, treatment and bioluminescent readouts for HepG2 cell spheroids and mice infected with P. berghei-Luc. B Dose−response curves and IC50 determinations of M5717 (pink) and atovaquone (gray; positive control) in HepG2 spheroids infected by P. berghei-Luc under static conditions at 2.5 × 104 cell/well in a 1:2 cell:spz ratio. The dots and error bar represents mean and standard deviation from three independent experiments

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