Table 1 Status of the Pfs25-based candidate vaccines currently in clinical pipeline including the vaccine type and trial identification number
Vaccine candidate | Type | Stage of development | Trial Identification number/reference |
|---|---|---|---|
Pfs25M-EPA/AS01 | Subunit vaccine | Phase 1 | NCT02942277 |
Pfs25EPA/Alhdrogel | Subunit vaccine | Phase 1 | NCT02334462 |
Pfs25EPA/Alhdrogel | Subunit vaccine | Phase 1 | NCT01867463 |
Pfs25 VLP-FhCMB | VLP vaccine | Phase 1 | NCT02013687 |
ChAd63 Pfs25-IMX313 ± MVA Pfs25-IMX313 | Viral vector & nanoparticle vaccine | Phase 1 | NCT02532049 |
Pfs25 /Montanide ISA 51 | Subunit vaccine | Phase 1 | [95] |
Pfs25-Pfs25 | Conjugate vaccine | Phase 1 | NCT00977899 |