Table 4 Predicted epitopes of Plasmodium tmCAs against MHC-II
CA class | MHC-II type | HLA allele | Peptide sequence | Predicted epitope for MHC-II | Scorea |
|---|---|---|---|---|---|
α-CA* (group 1) (W7JAI7) | DRB1 | HLA-DRB1*01:03 | 428-LRTIINVSSAVHVGS-442 | 428-LRTIINVSSAVHVGS-442 | 0.06 |
468-VFPIQVLISSAISNI-482 | 468-VFPIQVLISSAISNI-482 | 0.19 | |||
α-CA** (group 2) (Q8IHW5) | DRB1 | HLA-DRB1*01:02 | 424-SEKFLRTIINVSSAV-438 | 424-SEKFLRTIINVSSAV-438 | 0.86 |
η-CA*** (V7PFH4) | DQ | HLA-DQA1*01:01/DQB1*05:01 | 629-YGRVYLIQGFPVQLL-643 | 629-YGRVYLIQGFPVQLL-643 | 1.59 |