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Fig. 3 | Malaria Journal

Fig. 3

From: Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Fig. 3

Visual evaluation of potential matrix effects on Chiralcel OD-3R column (150 mm × 4.6 mm; I.D. 3 μm) at flow rate 1.0 mL/min. Injection of extracted blank human plasma (volunteer A) during post column infusion (10 μL/min) of primaquine (25 ng/mL) and carboxyprimaquine (50 ng/mL). The lower chromatogram represents the extracted ion chromatogram (EIC) of PRQ and upper chromatogram represents the extracted ion chromatogram of CPRQ. The arrows indicate the retention times for ( ±)-primaquine and ( ±)-carboxyprimaquine

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Malaria Journal

ISSN: 1475-2875

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