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Fig. 5 | Malaria Journal

Fig. 5

From: Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Fig. 5

Visual evaluation of potential matrix effects on the Hypersil Gold column (100 mm × 4.6 mm; I.D. 3 μm) at a flow rate of 0.5 mL/min. Injection of extracted blank human plasma (volunteer A) during post-column infusion (10 μL/min) of primaquine (10 ng/mL) and carboxyprimaquine (20 ng/mL). The upper chromatogram represents the extracted ion chromatogram (EIC) of PRQ and lower chromatogram represents the extracted ion chromatogram of CPRQ. The arrows indicate the retention times for primaquine and carboxyprimaquine

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