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Table 3 The haplotypes of the pvmdr-1 gene in Republic of Korea from 2016 to 2017

From: Single nucleotide polymorphism analysis of pvmdr-1 in Plasmodium vivax isolated from military personnel of Republic of Korea in 2016 and 2017

 

K44

AAG

 → AAA

L493

TTA

 → CTA

T529

ACA

 → ACG

Y541C

TAC

 → TGC

G698S

GGC

 → AGC

L845F

CTC

 → TTC

M908L

ATG

 → CTG

T958M

ACG

 → ATG

F1076L

TTT

 → CTT

E1233

GAG

 → GAA

Frequency

2016

2017

Type 0

–

–

–

–

AGC

TTC

CTG

ATG

CTT

–

1

0

Type 1

AAA

–

–

–

AGC

TTC

CTG

ATG

CTT

–

1

8

Type 2

AAA

–

–

–

AGC

TTC

CTG

ATG

CTT

GAA

3

16

Type 3

–

CTA

ACG

–

AGC

TTC

CTG

ATG

CTT

GAA

5

14

Type 4

–

–

ACG

–

AGC

TTC

CTG

ATG

CTT

–

10

14

Type 5

–

–

ACG

TGC

AGC

TTC

CTG

ATG

CTT

–

0

1

           

20

53

  1. All haplotypes (Type 0 to Type 5) contains quintuple non-synonymous SNPs (G689S, L845F, M908L, T958M and F1076L, marked in bold), novel non-synonymous SNP (Y541C), or synonymous SNPs (K44, L493, T529 and E1233) from 2016 to 2017. The frequency of each type was listed